Kirkstall’s Inter-connected cell culture system can be used for many bio-pharma applications:
Drug development Inter-connected cell culture systems provide a highly cost effective and accurate formulation screen before animal or human clinical trails. Regenerative medicine The advanced tissue culture environment allows faster growth of more physiologically accurate tissue to produce for example cartilage, or cardiac tissue. Safety and Toxicity screening Multi-chamber interconnected culture of different cell types allows cell-to-cell signalling providing a more physiologically accurate models of inflammatory or immune response than cells grown in multiwell plates. ADME studies Re-circulating perfusion systems with cells from the liver or pancreas can be included in the same system as target organ cells giving more realistic metabolic data. Disease modelling In vitro models of disease, such as glaucoma or hypertension can be created within the system by allowing pressure or flow stress to be applied to the cultured tissue. Stem cell research Culture conditions can be regulated and modulated in an accurate and reproducible way giving better control on lineage, controlling the phonotype that the stem cell adopts.
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